Endocrinology Test
1.
The medical treatment in microprolactinomas:
is indicated as a second line therapy only if surgery failed
includes dopamine agonists
can increase the tumoral volume
acts on the dimerization of prolactin receptor
includes somatostatin analogues
0
1
0
0
0
2.
In pituitary insufficiency the most severe insufficiency is induced by the deficiency of :
GH
TSH
ACTH
Prolactin
IGF-1
0
0
1
0
0
3.
Primary hyperparathyroidism associates:
hypercalcemia and hyperphosphoremia
increased serum PTH and hypercalcemia
increased serum PTH with hypocalcemia
hypercalcemia and low serum PTH
hypocalciuria
0
1
0
0
0
4.
The GH systemic effect is mediated by:
IGF1 (somatomedine)
TGF (transforming growth factor)
cortisol
gonadotrop releasing hormone (GHRH)
ARN
1
0
0
0
0
5.
In toxic adenoma the 1st line treatment is:
medical treatment with antithyroid drugs
definitive cure of hyperthyroidism
chronic treatment
no treatment is needed
conventional radiotherapy
0
1
0
0
0
6.
In GH deficiency in children:
Depot long acting preparation are needed
supplemental therapy is needed
the responsiveness in the first years of treatment
the used supplemental dose is unique
treatment initiation should be done as soon as possible ideally before age of 14
0
1
1
0
1
7.
Which of the following statements regarding corticotropin-releasing hormone are true:
its secretion is maximum at 1 a.m.
it increases gradually during the afternoon
it stimulates the POMC secretion in the anterior pituitary
the stress inhibits the release of CRH
mediates the physiological response to stress
0
1
1
0
1
8.
In cases of glucocorticoid excess suspicion confirmation tests are made with:
midnight inhibition test with 1 mg Dexamethasone
2 days inhibition test with Dexamethasone
insulin inhibition test
insulin stimulation test
glucose inhibition test
1
1
0
0
0
9.
The following are true regarding diagnostic of renal diabetes insipidus:
the levels of AVP (arginine vasopressin) are undetectable
there is no response to AVP administration regarding urine osmolality
there is a response after AVP administration regading urine osmolality
the free water clearance is negative
the free water clearance is positive
0
1
0
0
1
10.
Lab exam in Cushing’s shows:
low ACTH in corticotherapy
low ACTH in ectopic Cushing’s syndrome
low cortisol in ACTH-secreting pituitary adenoma
high serum cortisol in ectopic ACTH secretion
low ACTH in glucocorticoid secretory adrenal adenoma
1
0
0
1
1
11.
Sporadic hyperparathyroidism :
has higher prevalence in males
is asymptomatic in 60% of cases
typical parathyroid adenoma
typical diffuse parathyroid hyperplasia
maximum incidence around 3rd life decade
0
1
1
0
1
12.
Absolute contraindication for combine oral contraceptive use are:
light altered hepatic function
thromboembolic disease
breast cancer
any nodular breast pathology
smoker over 35 years of age
0
1
1
0
0
13.
Type I of primary osteoporosis:
appears after age of 75-80 years
affects especially postmenopausal women
associates an increased incidence of femoral neck fractures
bone resorption is increased significantly
increased risk of vertebral fractures
0
1
0
1
1
14.
The clinical suggestive features for thyroid malignancy are:
Rapid increase in thyroid nodule
Hoarseness
Regional adenopathies
Stable nodules in volume and shape
No positive changes on palpation
1
1
1
0
0
15.
In cases of vitamin D deficiency special situations with atypical vitamin D needs are:
obese patients
postmenopausal women
hypoanabolic cases
bariatric surgery cases
pregnant women
1
0
0
1
0
16.
SIADH syndrome appears in the following circumstances:
tumoral ectopic AVP secretion
central nervous system disorders: infections degenerative diseases
loss of AVP secretion
head trauma
hypoladosteronsimus
1
0
0
1
0
17.
Differential diagnostic of gigantism has to be made with:
Constitutional increased height
Marfan Sd.
Klinefelter sd.
Constitutional growth delay
Hypothyroidism
1
1
1
0
0
18.
Bone quality is dependent of:
genetic factors
nutritional factors
educational factors
mechanical factors
environmental factors
1
1
0
1
0
19.
The laboratory and paraclinical evaluation in parathyroid insufficiency show:
hypocalcemia
hypophosphatemia
hypocalciuria
hypophosphaturia
osteopenia
1
0
1
1
0
20.
In primary hyperparathyroidism laboratory tests show:
decreased phosphaturia
hypercalciuria
hyperphosphatemia
high serum level of 25 hydroxycholecalciferol
low phosphatemia
0
1
0
0
1
21.
Which statements are true about toxic adenoma:
can associate exophthalmos
is a benign thyroid nodule
anti TSH receptor antibodies are positive
the adenoma secretes uncontrolled T3 and T4
the goiter can be diffuse or nodular
0
1
0
1
0
22.
Which statements are true about glucocorticoid replacement therapy:
the replacement doses are divided in 3 equal dose
the replacement doses are divided in 1/2 morning + 1/2 at noon
hydrocortisone and cortisone acetate preparation are preferred
mineralocorticoid replacement is needed in all secondary insufficiency cases
mineralocorticoid replacement is needed in some of the primary insufficiency cases
1
0
1
0
1
23.
The following situations can induce hypertension:
hyperaldosteronism
hypothyroidism
diabetes insipidus
contraceptives administration
transsphenoidal adenomectomy
1
1
0
1
0
24.
Immunological evaluation of thyroid diseases comprise:
titer of autoimmune antithyroid antibodies
fibrinogen
titer of anti TSH receptor antibodies
HLA evaluation
titers of anticalcitonine antibodies
1
0
1
0
0
25.
Which statements regarding differentiated thyroid cancer are true:
I131 can be administered before total thyroidectomy to shrink the tumor
arises from thyroidal epithelial cells
the diagnostic marker is represented by serum thyroglobulin
arises from thyroidal parafollicular cells
medical treatment includes levothyroxine in suppressive doses
0
1
1
0
1