Endocrinology Test
1.
Zona reticularis:
Is part of the adrenal medulla
Is part of the parathyroid inner structure
Is secreting aldosterone
Is secreting glucocorticoids and androgens
Is present intranatal
0
0
0
1
0
2.
The following is false regarding nonfunctional pituitary adenoma:
no active hormonal secretion
PRL only secretion
associates functional tumoral syndrome
severity of the tumor does not correlate with tumor size
frontal lobe compression induces personality disorders
0
1
0
0
0
3.
The most common form of thyrotoxicosis is:
thyrotoxicosis factitia after levothyroxine administration
subacute thyroiditis
Graves’ disease
toxic adenoma
Hashimoto’s thyroiditis
0
0
1
0
0
4.
The differential diagnostic of hypocalcaemia is made with:
hyperthyroidism
hypomagnesemia
hypermagnesemia
hyperkalemia
respiratory acidosis
0
1
0
0
0
5.
The typical sequence of hormonal loss in hypopituitarism is:
GH TSH ACTH PRL LH/FSH
GH LH/FSH TSH ACTH PRL
ACTH PRL LH/FSH GH TSH
ACTH GH TSH PRL LH/FSH
TSH PRL LH/FSH ACTH GH
0
1
0
0
0
6.
The following are true regarding diagnostic of renal diabetes insipidus:
the levels of AVP (arginine vasopressin) are undetectable
there is no response to AVP administration regarding urine osmolality
there is a response after AVP administration regading urine osmolality
the free water clearance is negative
the free water clearance is positive
0
1
0
0
1
7.
Conditions associated with thyrotoxicosis are:
sub acute thyroiditis
medullary thyroid carcinoma
thyroid lymphoma
toxic adenoma
Amiodarone treatment
1
0
0
1
1
8.
In case of prolactinoma the endocrine syndrome in males comprise:
hypogonadism
hypothyroidism
normal fertility
infertility
altered libido
1
0
0
1
1
9.
The following are true regarding fine needle aspiration for thyroid nodules:
is considered the golden standard diagnostic tool
is reported as BETHESDA system
is inferior to ultrasound evaluation
follicular neoplasia is the most important diagnostic limitation
has to be performed in any thyroid nodule
1
1
0
0
0
10.
In Graves disease the indications for radioactive iodine treatment are:
children
old women
associated nodular lesions
no response to 1st line treatment in 1 months
no response to 1st line treatment in 1.5 years
0
1
0
0
1
11.
Testosterone has the following physiological effects:
aggravates osteoporosis
has anabolic effects on erythropoiesis
present anabolic effects on bone
promotes gynecomastia
inhibits the breast development
0
1
1
0
1
12.
Lab exam in Cushing’s shows:
low ACTH in corticotherapy
low ACTH in ectopic Cushing’s syndrome
low cortisol in ACTH-secreting pituitary adenoma
high serum cortisol in ectopic ACTH secretion
low ACTH in glucocorticoid secretory adrenal adenoma
1
0
0
1
1
13.
The endocrine complications of corticotherapy are:
diabetes
obesity
hypertension
suppression of physiological adrenal secretion
hypogonadism
0
0
0
1
1
14.
Laboratory tests for positive diagnosis in pheocromocytoma can reveal:
high ACTH
high plasma free metanephrines
high serum sodium
high serum potassium
high chromogranin A
0
1
0
0
1
15.
The clinical picture in chronic primary adrenal insufficiency includes:
pale skin
gall bladder hyperactivity
hirsutism
pubic and axillary hair loss
weight loss
1
0
0
1
1
16.
In pregnant women with untreated hypothyroidism the following are valid:
increased frequency of spontaneous abortions
increased premature risk
maternal hyperthyroidism
fetal hyperthyroidism
altered cognition of the fetus
1
1
0
0
1
17.
The control mechanisms of arginine vasopressin release include:
plasma osmolality change
long negative feedback loop
natural labour
volemic changes
suckling
1
0
0
1
0
18.
The corticotroph line insufficiency:
is treated with mineralocorticoid replacement therapy
is confirmed by ACTH stimulation test
is confirmed by CRH /insulin stimulation test
always has to be treated first
active follow up is make by measuring FT4 values
0
1
1
1
0
19.
The following regarding pituitary are true:
the posterior lobe regulates the main endocrine glands
the vascularization of the anterior lobe is represented by a capillary network
the posterior lobe contains the axons from the supraoptic and paraventricular nuclei
the posterior lobe contains glandular cells
hypothalamus controls the entire pituitary throught neurohormones release in the portal vein system
0
1
1
0
0
20.
In case of gonadotroph insufficiency in females the supplemental therapy has the following contraindications:
breast cancer
anemia
endometrial cancer
arterial tromboembolism
any breast solid nodules
1
0
1
1
0
21.
Amiodarone induced thyrotoxicosis:
is always a hyper production form of hyperthyroidism
can be a lesional hyperthyroidism
is more frequent in preexisting thyroid diseases
in lesional types is treated with anti-inflammatory medication
in lesional types is treated with antithyroid medication
0
1
1
1
0
22.
In primary hypothyroidism laboratory investigations can reveal:
low TSH
positive antithyroid antibodies
increased TSH
low serum thyroid hormones
stimulatory anti TSH antibodies in high titres
0
1
1
1
0
23.
Which statements regarding pheocromocytoma are true:
usually is an unilateral tumor
the tumor is derived from adrenal chromaffin cells
the origin is in the glomerular zone of adrenal cortex
betablockers are 1st line medical treatment agents
the hypertensive crisis can be triggered by specific drugs foods or activities
1
1
0
0
1
24.
Stimulatory neurohormones (promoting) from the hypothalamus are represented by:
corticotropin-releasing hormone
arginin vasopressin
oxytocin
somatostatin
growth hormone-releasing hormone
1
0
0
0
1
25.
The treatment options in Cushing’s include the following:
in cortisol secreting adenoma radiotherapy is a second line treatment
in Cushing’s disease transsphenoidal microsurgery is indicated
in cortisol secreting adenoma bilateral adrenalectomy is indicated
medical treatment includes drugs that inhibit cortisol synthesis
dopamine agonists
0
1
0
1
0