Endocrinology Test
1.
Primary hyperparathyroidism associates:
hypercalcemia and hyperphosphoremia
increased serum PTH and hypercalcemia
increased serum PTH with hypocalcemia
hypercalcemia and low serum PTH
hypocalciuria
0
1
0
0
0
2.
The most common form of thyrotoxicosis is:
thyrotoxicosis factitia after levothyroxine administration
subacute thyroiditis
Graves’ disease
toxic adenoma
Hashimoto’s thyroiditis
0
0
1
0
0
3.
Autocrine effect represents:
action on self
juxtacellular action
local action on another type of cell different from the secretion one
remote effect after excretion outside the body
remote effect after excretion into the interstitial space
1
0
0
0
0
4.
The medical treatment in microprolactinomas:
is indicated as a second line therapy only if surgery failed
includes dopamine agonists
can increase the tumoral volume
acts on the dimerization of prolactin receptor
includes somatostatin analogues
0
1
0
0
0
5.
The GH systemic effect is mediated by:
IGF1 (somatomedine)
TGF (transforming growth factor)
cortisol
gonadotrop releasing hormone (GHRH)
ARN
1
0
0
0
0
6.
The diagnostic of multinodular toxic goiter is suggested by:
Polinodular goiter on ultrasound
Diffuse hyper vascularization on ultrasound
Positive antithyroid antibodies
hyperactive nodule with suppressed surrounding on the scintigraphy
multinodular hyperactive nodules on scintigraphy with patchy aspect
1
0
0
0
1
7.
In cases of glucocorticoid excess suspicion confirmation tests are made with:
midnight inhibition test with 1 mg Dexamethasone
2 days inhibition test with Dexamethasone
insulin inhibition test
insulin stimulation test
glucose inhibition test
1
1
0
0
0
8.
In GH deficiency in children:
Depot long acting preparation are needed
supplemental therapy is needed
the responsiveness in the first years of treatment
the used supplemental dose is unique
treatment initiation should be done as soon as possible ideally before age of 14
0
1
1
0
1
9.
The treatment options in Cushing’s include the following:
in cortisol secreting adenoma radiotherapy is a second line treatment
in Cushing’s disease transsphenoidal microsurgery is indicated
in cortisol secreting adenoma bilateral adrenalectomy is indicated
medical treatment includes drugs that inhibit cortisol synthesis
dopamine agonists
0
1
0
1
0
10.
Which of the following statements regarding the treatment of chronic adrenal insufficiency are true:
hydrocortisone can be administered
Prednisone should be given daily in 3 equal doses after meals
the treatment should be administered 1-2 years
the dose of prednisone is 20-25 mg/day
mineralocorticoid substitution – Fludrocortison
1
1
0
0
0
11.
Lab exam in Cushing’s shows:
low ACTH in corticotherapy
low ACTH in ectopic Cushing’s syndrome
low cortisol in ACTH-secreting pituitary adenoma
high serum cortisol in ectopic ACTH secretion
low ACTH in glucocorticoid secretory adrenal adenoma
1
0
0
1
1
12.
In pituitary adenoma the clinical symptoms can be grouped as following:
functional sd
compression sd
metabolic sd
inhibition sd
emdocrine sd
0
1
1
0
1
13.
Which of the following thyroid ultrasound signs are suspicious for malignancy in a nodule:
thin halo
hyperechogenity
“taller than wide†shape
calcifications
subcapsular localisation
0
0
1
1
1
14.
The classification of thyroid cancer comprises:
follicular carcinoma
adenocarcinoma
sarcoma
Hurthle cell neoplasia
medullary carcinoma
1
0
0
1
1
15.
Causes of primary hypothyroidism are represented by:
sub acute thyroiditis
autoimmune thyroid disease
acute thyroiditis
TSH secreting pituitary adenoma
postpartum pituitary necrosis
1
1
0
0
0
16.
The differential diagnostic of prolactinoma has to be made with:
GH secreting adenoma
cases with pituitary stalk deviation
gonadotrop secreting tumors
functional causes: stress sleep food medication
hypothyroidism
0
1
0
1
1
17.
The clinical suggestive features for thyroid malignancy are:
Rapid increase in thyroid nodule
Hoarseness
Regional adenopathies
Stable nodules in volume and shape
No positive changes on palpation
1
1
1
0
0
18.
The mortality rate in differentiated thyroid cancer at 5 years are:
0% in stage 1 disease
0% in stage 3 of the disease
5% in stage 3 of the disease
50% in stage 4 of the disease
95% in stage 4 of the disease
1
0
0
1
0
19.
In pituitary tumors with compression of the cavernous sinus:
affects the cranial nerves III IV VI
induces diplopia ptosis or ophtamoplegia
induces headache
induces seizures
induces personality disorders
1
1
0
0
0
20.
Which statements regarding pheocromocytoma are true:
usually is an unilateral tumor
the tumor is derived from adrenal chromaffin cells
the origin is in the glomerular zone of adrenal cortex
usually are aggressive malignant tumors
the hypertensive crisis can be triggered by specific drugs foods or activities
1
1
0
0
1
21.
Laboratory exam in Graves’ disease shows:
low tryglicerides
hypercholesterolemia
hypoglycaemia
positive anti TSH receptor antibodies
low TSH
1
0
0
1
1
22.
In case of suspicion on GH hyper secretion:
glucose load inhibition test is performed
the GH level decrease after insulin test
arginine test is used
glucagon test is used
no GH suppression after 60 and 120 minutes is seen
1
0
0
0
1
23.
Bone quality is dependent of:
genetic factors
nutritional factors
educational factors
mechanical factors
environmental factors
1
1
0
1
0
24.
Type I of primary osteoporosis:
appears after age of 75-80 years
affects especially postmenopausal women
associates an increased incidence of femoral neck fractures
bone resorption is increased significantly
increased risk of vertebral fractures
0
1
0
1
1
25.
In Graves disease surgical treatment is indicated in:
is considered 1st line therapy
large thyroid glands
associated multinodular diseases
pregnant women regardless the pregnancy stage
allergies to medical treatment
0
1
1
0
1